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Hemopexin Protein (HPX) (His tag)

This Recombinant Hemopexin protein is expressed in HEK-293 Cells.
产品编号 ABIN7317735
发货至: 中国

Quick Overview for Hemopexin Protein (HPX) (His tag) (ABIN7317735)

抗原

See all Hemopexin (HPX) 蛋白
Hemopexin (HPX)

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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HEK-293 Cells

纯度

> 96 % as determined by reducing SDS-PAGE.
  • 标记

    This Hemopexin protein is labelled with His tag.

    原理

    Recombinant Human Hemopexin/HPX Protein (His Tag)(Active)

    序列

    Met 1-His 462

    产品特性

    A DNA sequence encoding the human HPX (NP_000604.1) (Met 1-His 462) with a C-terminal polyhistidine tag was expressed.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to bind protoporphyrin IX (PPPIX). Recombinant human Hemopexin binds > 10 μM PPPIX, resulting in a 50% decrease in the fluorescence signal of human Hemopexin.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Hemopexin (HPX)

    别名

    Hemopexin/HPX

    背景

    Background: GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane domains, three extracellular loops, three intracellular loops, an amino-terminal extracellular domain and an intracellular carboxyl terminus. It is thought that light acts as the activating stimulus of a G-protein-coupled receptor (GPCR). GPCRs are expected to have molecular function (G-protein coupled receptor activity) and to localize in various compartments (endoplasmic reticulum membrane, plasma membrane, integral to membrane). Family B of the GPCRs is a small but structurally and functionally diverse group of proteins that includes receptors for polypeptide hormones, molecules thought to mediate intercellular interactions at the plasma membrane and a group of Drosophila proteins that regulate stress responses and longevity. GPR114 contains 1 GPS domain. GPR114 gene has been proposed to participate in processes (G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway).

    Synonym: Hemopexin,Hpx,Hpxn

    分子量

    50.7 kDa

    NCBI登录号

    NP_000604

    途径

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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