HMOX1 蛋白
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- 抗原 See all HMOX1 蛋白
- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human HO-1/HMOX1 Protein
- 序列
- Met 1-Thr 261
- 产品特性
- Recombinant Human Heme Oxygenase 1 is produced by our E.coli expression system and the target gene encoding Met1-Thr261 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HMOX1 蛋白
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Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-266) protein (His tag)
HMOX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-261) protein (His tag)HMOX1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-267) protein (His-IF2DI Tag)HMOX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-288) protein (GST tag)HMOX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-110) protein (GST tag)HMOX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Heme Oxygenase (Decycling) 1 (HMOX1) (partial) protein (His tag)HMOX1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90% WB, SDS
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-289) protein (Strep Tag)Crystallography grade HMOX1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
- 别名
- HO-1/HMOX1 (HMOX1 产品)
- 别名
- HMOX1 Protein, ARABIDOPSIS THALIANA HEME OXYGENASE 1 Protein, ATHO1 Protein, F18A8.4 Protein, F18A8_4 Protein, GENOMES UNCOUPLED 2 Protein, GUN2 Protein, HEME OXYGENASE Protein, HEME OXYGENASE 1 Protein, HEME OXYGENASE 6 Protein, HO1 Protein, HY1 Protein, HY6 Protein, PLASTID HEME OXYGENASE Protein, REVERSAL OF THE DET PHENOTYPE 4 Protein, HO-1 Protein, wu:fc27c04 Protein, zgc:65984 Protein, D8Wsu38e Protein, Hemox Protein, Hmox Protein, Hsp32 Protein, HEOXG Protein, Heox Protein, Ho-1 Protein, Ho1 Protein, hsp32 Protein, MGC132176 Protein, Hmox1 Protein, HMOX1D Protein, HSP32 Protein, bK286B10 Protein, heme oxygenase 1 Protein, Plant heme oxygenase (decyclizing) family protein Protein, Heme oxygenase Protein, heme oxygenase Protein, heme oxygenase 1, chloroplastic Protein, heme oxygenase 1a Protein, heme oxygenase 1 L homeolog Protein, HMOX1 Protein, TED4 Protein, ho1 Protein, P9301_RS17555 Protein, A9601_RS17590 Protein, MAE_RS06565 Protein, HO1 Protein, hmox1a Protein, CPE0214 Protein, Cyan7425_2962 Protein, Hmox1 Protein, hmox1.L Protein, AM1_C0205 Protein, CC1G_11686 Protein, CpipJ_CPIJ007246 Protein
- 背景
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Background: Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.
Synonym: Heme Oxygenase 1, HO-1, HMOX1, HO, HO1
- 分子量
- 29.9 kDa
- UniProt
- P09601
- 途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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