HMOX1 蛋白
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北京 101111
Quick Overview for HMOX1 蛋白 (ABIN7318568)
抗原
See all HMOX1 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human HO-1/HMOX1 Protein
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序列
- Met 1-Thr 261
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产品特性
- Recombinant Human Heme Oxygenase 1 is produced by our E.coli expression system and the target gene encoding Met1-Thr261 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-267) protein (His-IF2DI Tag)
HMOX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-261) protein (His-IF2DI Tag)HMOX1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-266) protein (His tag)HMOX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-288) protein (GST tag)HMOX1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
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别名
- HO-1/HMOX1
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背景
- HMOX1,HO,HO-1,HO1,Heme Oxygenase 1,Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.
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分子量
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Calculated MW: 29.9 kDa
Observed MW: 30 kDa
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基因ID
- 3162
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UniProt
- P09601
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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