GAMT Protein (His tag)
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北京 101111
Quick Overview for GAMT Protein (His tag) (ABIN7318555)
抗原
See all GAMT 蛋白蛋白类型
宿主
资源
纯度
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标记
- This GAMT protein is labelled with His tag.
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原理
- Recombinant Human GAMT Protein (His Tag)
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序列
- Met 1-Gly236
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产品特性
- Recombinant Human Guanidinoacetate N-methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236), (full length) protein (His tag)
GAMT 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GAMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)GAMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag)GAMT 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mMDTT, pH 8.0 .
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
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别名
- GAMT
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背景
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Background: GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.
Synonym: Guanidinoacetate N-methyltransferase, GAMT, PIG2,TP53I2
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分子量
- 29.5 kDa
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UniProt
- Q14353
抗原
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