GDF11 蛋白
Quick Overview for GDF11 蛋白 (ABIN7318551)
抗原
See all GDF11 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human GDF11/BMP-11 Protein
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序列
- Asn299-Ser407
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产品特性
- Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- GDF11 (Growth Differentiation Factor 11 (GDF11))
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别名
- GDF11/BMP-11
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背景
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Background: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
Synonym: Growth/differentiation factor 11,GDF-11,Bone morphogenetic protein 11,BMP-11
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分子量
- 12.6 kDa
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UniProt
- O95390
抗原
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