GDF11 Protein (AA 299-407)
This Recombinant GDF11 protein is expressed in HEK-293 Cells.
产品编号 ABIN7318551
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for GDF11 Protein (AA 299-407) (ABIN7318551)
抗原
See all GDF11 蛋白
GDF11
(Growth Differentiation Factor 11 (GDF11))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 299-407
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原理
- Recombinant Human GDF11/BMP-11 Protein
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序列
- Asn299-Ser407
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产品特性
- Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 % glycerol, pH 7.4.
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- GDF11 (Growth Differentiation Factor 11 (GDF11))
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别名
- GDF11/BMP-11
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背景
- BMP-11,Bone morphogenetic protein 11,GDF-11,Growth/differentiation factor 11,Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
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分子量
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Calculated MW: 12.5 kDa
Observed MW: 13-20 kDa
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基因ID
- 10220
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UniProt
- O95390
抗原
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