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GCDH Protein (His tag)

This Recombinant GCDH protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318540
发货至: 中国

Quick Overview for GCDH Protein (His tag) (ABIN7318540)

抗原

See all GCDH 蛋白
GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

蛋白类型

Recombinant

宿主

  • 6
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资源

  • 5
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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This GCDH protein is labelled with His tag.

    原理

    Recombinant Human GCDH Protein (His Tag)

    序列

    Arg45-Lys438

    产品特性

    Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg45-Lys438 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

    别名

    GCDH

    背景

    Background: Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.

    Synonym: Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH

    分子量

    45.0 kDa

    UniProt

    Q92947
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