GCDH Protein (His tag)
Quick Overview for GCDH Protein (His tag) (ABIN7318540)
抗原
See all GCDH 蛋白蛋白类型
宿主
资源
纯度
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标记
- This GCDH protein is labelled with His tag.
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原理
- Recombinant Human GCDH Protein (His Tag)
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序列
- Arg45-Lys438
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产品特性
- Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg45-Lys438 is expressed with a 6His tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- GCDH (Glutaryl-CoA Dehydrogenase (GCDH))
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别名
- GCDH
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背景
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Background: Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.
Synonym: Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH
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分子量
- 45.0 kDa
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UniProt
- Q92947
抗原
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