Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (AA 2-515) (His tag)
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北京 101111
Quick Overview for Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (AA 2-515) (His tag) (ABIN7318537)
抗原
See all Glucose-6-Phosphate Dehydrogenase (G6PD) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 2-515
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标记
- This Glucose-6-Phosphate Dehydrogenase protein is labelled with His tag.
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原理
- Recombinant Human G6PD Protein (His Tag)
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序列
- Ala2-Leu515
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产品特性
- Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 15 % Trehalose, 150 mM NaCl, 0.05 % Tween 80, pH 5.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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别名
- G6PD
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背景
- G6PD,Glucose-6-Phosphate 1-Dehydrogenase,Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
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分子量
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Calculated MW: 60.2 kDa
Observed MW: 55-62 kDa
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基因ID
- 2539
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UniProt
- P11413
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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