Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag)
Quick Overview for Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag) (ABIN7318537)
抗原
See all Glucose-6-Phosphate Dehydrogenase (G6PD) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Glucose-6-Phosphate Dehydrogenase protein is labelled with His tag.
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原理
- Recombinant Human G6PD Protein (His Tag)
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序列
- Ala2-Leu515
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产品特性
- Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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别名
- G6PD
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背景
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Background: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
Synonym: Glucose-6-Phosphate 1-Dehydrogenase, G6PD
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分子量
- 60.2 kDa
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UniProt
- P11413
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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