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GABA Protein (GST tag)

This Recombinant GABA protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318511
发货至: 中国
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Quick Overview for GABA Protein (GST tag) (ABIN7318511)

抗原

GABA (gamma-Aminobutyric Acid (GABA))

蛋白类型

Recombinant

宿主

  • 1
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资源

  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This GABA protein is labelled with GST tag.

    原理

    Recombinant Human GABA Protein (GST Tag)

    序列

    Met 1-Lys117

    产品特性

    Recombinant Human GABA(A) Receptor-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys117 is expressed with a GST tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 200 mM NaCl, pH 7.5.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    GABA (gamma-Aminobutyric Acid (GABA))

    别名

    GABA

    物质类

    Amino Acid

    背景

    GABA(A) Receptor-Associated Protein,GABARAP,GABARAP Protein,HCG1987397 Isoform CRA_b,Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. GABARAP clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. An important inhibitory neurotransmitter, GABA, acts on GABA receptors that are ubiquitously expressed in the CNS. GABARAP has been shown to play a important role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

    分子量

    Calculated MW: 40.2 kDa

    Observed MW: 37 kDa

    UniProt

    Q6IAW1
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