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Fibrillin 1 Protein (FBN1) (AA 2732-2871) (His tag)

This Recombinant Fibrillin 1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7320523
发货至: 中国
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Quick Overview for Fibrillin 1 Protein (FBN1) (AA 2732-2871) (His tag) (ABIN7320523)

抗原

See all Fibrillin 1 (FBN1) 蛋白
Fibrillin 1 (FBN1)

蛋白类型

Recombinant

宿主

  • 10
  • 4
  • 4
小鼠

资源

  • 14
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 80 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 2732-2871

    标记

    This Fibrillin 1 protein is labelled with His tag.

    原理

    Recombinant Mouse Fibrillin-1/FBN1 Protein (His Tag)

    序列

    Ser2732-His2871

    产品特性

    Recombinant Mouse Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Fibrillin 1 (FBN1)

    别名

    Fibrillin-1/FBN1

    背景

    Fibrillin,Asprosin,Fibrillin-1,Fbn-1,Fbn1,ACMICD,ECTOL1,FBN,GPHYSD2,MASS,MFS1,OCTD,SGS,SSKS,WMS,WMS2,Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.

    分子量

    Calculated MW: 16.9 kDa

    Observed MW: 30 kDa

    UniProt

    Q61554

    途径

    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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