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FABP5 蛋白

This Recombinant FABP5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7317355
发货至: 中国
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Quick Overview for FABP5 蛋白 (ABIN7317355)

抗原

See all FABP5 蛋白
FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

蛋白类型

Recombinant

宿主

  • 8
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资源

  • 11
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大肠杆菌(E. Coli)

纯度

> 92 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human FABP5 Protein

    序列

    Met 1-Glu 135

    产品特性

    A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile 50 mM Tris, pH 8.0

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

    别名

    FABP5

    背景

    Background: Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.

    Synonym: Fatty Acid-Binding Protein Epidermal; Epidermal-Type Fatty Acid-Binding Protein; E-FABP; Fatty Acid-Binding Protein 5; Psoriasis-Associated Fatty Acid-Binding Protein Homolog; PA-FABP; FABP5

    分子量

    15.2 kDa

    UniProt

    Q01469
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