Quick Overview for ECM1 Protein (His tag) (ABIN7320312)
抗原
See all ECM1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This ECM1 protein is labelled with His tag.
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原理
- Recombinant Mouse ECM1 Protein (His Tag)(Active)
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序列
- Met 1-Glu 559
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产品特性
- A DNA sequence encoding the mouse ECM1 isoform 1 (Q61508-1) (Met 1-Glu 559) was expressed, fused with a polyhistidine tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to bind human MMP-9 in a functional ELISA.
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Extracellular Matrix Protein 1 (ECM1) (AA 24-210) protein (His-IF2DI Tag)
ECM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Extracellular Matrix Protein 1 (ECM1) (AA 1-540) protein (GST tag)ECM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Extracellular Matrix Protein 1 (ECM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ECM1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- ECM1 (Extracellular Matrix Protein 1 (ECM1))
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别名
- ECM1
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背景
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Background: Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.
Synonym: AI663821;p85
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分子量
- 62.5 kDa
抗原
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