DPP10 Protein (His tag)
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Quick Overview for DPP10 Protein (His tag) (ABIN7317488)
抗原
See all DPP10 蛋白蛋白类型
宿主
资源
纯度
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标记
- This DPP10 protein is labelled with His tag.
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原理
- Recombinant Human DPP10/DPRP3 Protein (His Tag)
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序列
- Leu 56-Glu 796
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产品特性
- A DNA sequence encoding the human DPP10 isoform 1 (Q8N608-1) extracellular domain (Leu 56-Glu 796) was expressed, with a polyhistidine tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Dipeptidylpeptidase 10 (DPP10) (AA 1-796) protein (GST tag)
DPP10 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Dipeptidylpeptidase 10 (DPP10) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DPP10 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- DPP10 (Dipeptidylpeptidase 10 (DPP10))
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别名
- DPP10/DPRP3
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背景
- DPL2,DPPY,DPRP-3,DPRP3,Inactive dipeptidyl peptidase 10, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP10, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP10 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
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分子量
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Calculated MW: 87.4 kDa
Observed MW: 90-110 kDa
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基因ID
- 57628
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UniProt
- Q8N608
抗原
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