DEFB4A 蛋白
Quick Overview for DEFB4A 蛋白 (ABIN7319217)
抗原
See all DEFB4A (DEFB4) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human β-Defensin 4A/DEFB4A Protein
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序列
- Gly24-Pro64
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产品特性
- Recombinant Human beta-Defensin 4A is produced by our E.coli expression system and the target gene encoding Gly24-Pro64 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Defensin, beta 4A (DEFB4) (Active) protein
DEFB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin, beta 4A (DEFB4) (AA 24-64) protein (His tag)DEFB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
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别名
- beta-Defensin 4A/DEFB4A
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背景
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Background: β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38 % and 33 % amino acid sequence identity with mouse and rat BD3, respectively.
Synonym: Beta-Defensin 4A, Beta-Defensin 2, BD-2, hBD-2, Defensin, Beta 2, Skin-Antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B
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分子量
- 4.3 kDa
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UniProt
- O15263
抗原
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