DEFB4A Protein (AA 24-64)
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北京 101111
Quick Overview for DEFB4A Protein (AA 24-64) (ABIN7319217)
抗原
See all DEFB4A (DEFB4) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 24-64
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原理
- Recombinant Human β-Defensin 4A/DEFB4A Protein
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序列
- Gly24-Pro64
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产品特性
- Recombinant Human beta-Defensin 4A is produced by our E.coli expression system and the target gene encoding Gly24-Pro64 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Defensin, beta 4A (DEFB4) (Active) protein
DEFB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin, beta 4A (DEFB4) (AA 24-64) protein (His-IF2DI Tag)DEFB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
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别名
- beta-Defensin 4A/DEFB4A
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背景
- BD-2,Beta 2,Beta-Defensin 2,Beta-Defensin 4A,DEFB102,DEFB2,DEFB4,DEFB4A,DEFB4B,Defensin,SAP1,Skin-Antimicrobial Peptide 1,hBD-2,β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38 % and 33 % amino acid sequence identity with mouse and rat BD3, respectively.
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分子量
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Calculated MW: 4.3 kDa
Observed MW: 9 kDa
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基因ID
- 100289462
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UniProt
- O15263
抗原
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