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beta Defensin 1 蛋白

This Recombinant beta Defensin 1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7319215
发货至: 中国

Quick Overview for beta Defensin 1 蛋白 (ABIN7319215)

抗原

See all beta Defensin 1 (DEFB1) 蛋白
beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

蛋白类型

Recombinant

宿主

  • 10
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  • 1
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资源

  • 15
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  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human β-Defensin 1/DEFB1 Protein

    序列

    Gly22-Lys68

    产品特性

    Recombinant Human beta-Defensin 1 is produced by our E.coli expression system and the target gene encoding Gly22-Lys68 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

    别名

    beta-Defensin 1/DEFB1

    背景

    Background: β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.

    Synonym: Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1

    分子量

    5.1 kDa

    UniProt

    P60022
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