beta Defensin 1 Protein (AA 22-68)
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北京 101111
Quick Overview for beta Defensin 1 Protein (AA 22-68) (ABIN7319215)
抗原
See all beta Defensin 1 (DEFB1) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 22-68
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原理
- Recombinant Human β-Defensin 1/DEFB1 Protein
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序列
- Gly22-Lys68
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产品特性
- Recombinant Human beta-Defensin 1 is produced by our E.coli expression system and the target gene encoding Gly22-Lys68 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
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别名
- beta-Defensin 1/DEFB1
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背景
- BD-1,BD1,Beta-Defensin 1,DEFB1,Defensin Beta 1,HBD1,hBD-1,β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.
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分子量
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Calculated MW: 5.1 kDa
Observed MW: 6 kDa
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基因ID
- 1672
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UniProt
- P60022
抗原
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