Quick Overview for CST3 Protein (His tag) (ABIN7195330)
抗原
See all CST3 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CST3 protein is labelled with His tag.
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原理
- Recombinant Rat Cystatin C/CST3 Protein (His Tag)
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序列
- Met 1-Ala 140
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产品特性
- A DNA sequence encoding the rat CST3 (P14841-1) (Met 1-Ala 140) was fused with a polyhistidine tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
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Cystatin C (CST3) (AA 29-148) protein (His tag)
CST3 宿主: 兔 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cystatin C (CST3) (AA 29-146) protein (His tag)CST3 宿主: Pig 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cystatin C (CST3) (AA 1-146) protein (GST tag)CST3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cystatin C (CST3) (AA 21-140) (Active) protein (His tag)CST3 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS, EAA Active
Cystatin C (CST3) (AA 21-140) (Active) protein (His tag)CST3 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM HEPES, 150 mM NaCl, pH 7.0
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CST3 (Cystatin C (CST3))
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别名
- Cystatin C/CST3
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背景
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Background: Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein which has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.
Synonym: Aa1249,Ab1-341,Ab2-196,Ac1-114,Ac1262,Ac2-069,Ba2-693
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分子量
- 14.7 kDa
抗原
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