Contactin 4 Protein (CNTN4) (His tag)
This Recombinant Contactin 4 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7317984
发货至:
中国
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Quick Overview for Contactin 4 Protein (CNTN4) (His tag) (ABIN7317984)
抗原
See all Contactin 4 (CNTN4) 蛋白
Contactin 4 (CNTN4)
蛋白类型
Recombinant
宿主
人
资源
Baculovirus infected Insect Cells
纯度
> 90 % as determined by reducing SDS-PAGE.
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标记
- This Contactin 4 protein is labelled with His tag.
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原理
- Recombinant Human Contactin 4/CNTN4 Protein (His Tag)
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序列
- Met 1-Ser 1000
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产品特性
- A DNA sequence encoding the mature form of human CNTN4 isoform 1 (Q8IWV2-1) (Met 1-Ser 1000) was fused with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Contactin 4 (CNTN4) (AA 1-697) protein (GST tag)
CNTN4 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Contactin 4 (CNTN4) proteinCNTN4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Contactin 4 (CNTN4)
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别名
- Contactin 4/CNTN4
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背景
- AXCAM,BIG-2,Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences.
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分子量
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Calculated MW: 110 kDa
Observed MW: 120-130 kDa
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基因ID
- 152330
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UniProt
- Q8IWV2
抗原
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