CTGF Protein (AA 27-180)
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北京 101111
Quick Overview for CTGF Protein (AA 27-180) (ABIN7318333)
抗原
See all CTGF 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 27-180
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原理
- Recombinant Human CTGF/CCN2 Protein
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序列
- Glu27-Ala180
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产品特性
- Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Glu27-Ala180 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CTGF (Connective Tissue Growth Factor (CTGF))
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别名
- CTGF/CCN2
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背景
- CCN family member 2,Connective tissue growth factor,Hypertrophic chondrocyte-specific protein 24,IBP-8,IGF-binding protein 8,IGFBP-8,Insulin-like growth factor-binding protein 8,CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
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分子量
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Calculated MW: 16.3 kDa
Observed MW: 16-25 kDa
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基因ID
- 1490
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UniProt
- P29279
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途径
- Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
抗原
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