CPLX2 Protein (His tag)
Quick Overview for CPLX2 Protein (His tag) (ABIN7317462)
抗原
See all CPLX2 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CPLX2 protein is labelled with His tag.
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原理
- Recombinant Human Complexin-2/CPLX2 Protein (His Tag)
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序列
- Asp 2-Lys 134
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产品特性
- A DNA sequence encoding the human CPLX2 (Q6PUV4-1) (Asp 2-Lys 134) was expressed, with a polyhistide tag at the N-terminus.
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Complexin 2 (CPLX2) (AA 1-134) protein (His tag)
custom-made CPLX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Complexin 2 (CPLX2) (AA 1-134) protein (His tag)custom-made CPLX2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Complexin 2 (CPLX2) protein (DYKDDDDK Tag)CPLX2 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Complexin 2 (CPLX2) proteinCPLX2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Complexin 2 (CPLX2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CPLX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Complexin 2 (CPLX2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CPLX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CPLX2 (Complexin 2 (CPLX2))
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别名
- Complexin-2/CPLX2
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背景
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Background: Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target SNARE complexes. Complexin 1 (CX1) and complexin 2 (CX2) are presynaptic proteins that modulate neurotransmitter release and are used as markers of inhibitory and excitatory synapses, respectively. CPLX2 is localized in pre-synaptic terminals in mature brain. The G71-P89 region of CPLX2 is essential and sufficient for preferential axonal distribution. CPLX2 participates in the Ca(2+)-sensitive regulatory pathway for zymogen granule exocytosis. Complexin-2 is a key player in normal neurological function, and its downregulation could lead to changes in neurotransmitter release sufficient to cause significant behavioural abnormalities such as depression. It is involved in synaptogenesis and the modulation of neurotransmitter release.
Synonym: 921-L,CPX-2,CPX2,Hfb1
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分子量
- 16.8 kDa
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途径
- Synaptic Vesicle Exocytosis
抗原
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