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CXCL2 蛋白

This anti-CXCL2 antibody (ABIN7320503) is a Escherichia coli (E. coli) antibody detecting CXCL2 in . Suitable for Mouse.
产品编号 ABIN7320503
发货至: 中国

Quick Overview for CXCL2 蛋白 (ABIN7320503)

抗原

See all CXCL2 蛋白
CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

蛋白类型

Recombinant

宿主

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小鼠

资源

  • 22
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大肠杆菌(E. Coli)

纯度

> 95 % as determined by SDS-PAGE
  • 原理

    Recombinant Mouse CXCL2/MIP-2 Protein

    序列

    Ala28-Asn100

    产品特性

    Recombinant Mouse C-X-C motif chemokine 2 is produced by our E.coli expression system and the target gene encoding Ala28-Asn100 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

    别名

    CXCL2/MIP-2

    背景

    Background: C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63 % aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

    Synonym: MIP-2, chemokine ligand 2, C-X-C motif chemokine 2, GRO beta, GRO2, GROB, Gro-beta, Growth-regulated protein beta, Macrophage Inflammatory Protein-2-alpha, melanoma growth stimulatory activity beta, cxcl2, MGSA-b, MGSA-beta, MIP2A, MIP2-alpha, SCYB2.

    分子量

    7.9 kDa

    UniProt

    P10889

    途径

    Cellular Response to Molecule of Bacterial Origin
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