CCL9 Protein (AA 22-122)
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北京 101111
Quick Overview for CCL9 Protein (AA 22-122) (ABIN7320489)
抗原
See all CCL9 (Ccl9) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 22-122
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原理
- Recombinant Mouse CCL9/MIP-1-γ Protein
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序列
- Gln22-Gln122
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产品特性
- Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CCL9 (Ccl9) (Chemokine (C-C Motif) Ligand 9 (Ccl9))
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别名
- CCL9/MIP-1-gamma
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背景
- C-C motif chemokine 9,CCF18,Macrophage inflammatory protein 1-gamma,Macrophage inflammatory protein-related protein 2,Scya10,Scya9 and CCL9.,Small-inducible cytokine A9,C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
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分子量
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Calculated MW: 11.6 kDa
Observed MW: 15 kDa
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UniProt
- P51670
抗原
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