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CCL9 Protein (AA 22-122)

This Recombinant CCL9 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7320489
发货至: 中国
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Quick Overview for CCL9 Protein (AA 22-122) (ABIN7320489)

抗原

See all CCL9 (Ccl9) 蛋白
CCL9 (Ccl9) (Chemokine (C-C Motif) Ligand 9 (Ccl9))

蛋白类型

Recombinant

宿主

  • 10
  • 2
小鼠

资源

  • 11
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 22-122

    原理

    Recombinant Mouse CCL9/MIP-1-γ Protein

    序列

    Gln22-Gln122

    产品特性

    Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, pH 8.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CCL9 (Ccl9) (Chemokine (C-C Motif) Ligand 9 (Ccl9))

    别名

    CCL9/MIP-1-gamma

    背景

    C-C motif chemokine 9,CCF18,Macrophage inflammatory protein 1-gamma,Macrophage inflammatory protein-related protein 2,Scya10,Scya9 and CCL9.,Small-inducible cytokine A9,C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.

    分子量

    Calculated MW: 11.6 kDa

    Observed MW: 15 kDa

    UniProt

    P51670
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