CD96 Protein (CD96) (His tag)
Quick Overview for CD96 Protein (CD96) (His tag) (ABIN7320155)
抗原
See all CD96 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CD96 protein is labelled with His tag.
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原理
- Recombinant Mouse CD96 Protein (His Tag)(Active)
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序列
- Met 1-Met 536
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产品特性
- A DNA sequence encoding the mouse CD96 (Q3U0X8) extracellular domain (Met 1-Met 536) was expressed, fused with a C-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA.2. Immobilized recombinant Mouse CD96 at 10 μg/ml (100 μl/well) can bind mouse PVR with a linear range of 6.4-160 ng/ml.
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CD96 (CD96) (AA 22-503) protein (His tag)
CD96 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD96 (CD96) (AA 22-503) protein (mFc Tag)CD96 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD96 (CD96) (AA 22-503), (C110S) protein (His tag)CD96 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD96 (CD96) (AA 22-502) protein (His tag)CD96 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD96 (CD96) (AA 22-536) protein (His tag)CD96 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD96 (CD96) (AA 22-503) protein (His-Avi Tag,Biotin)CD96 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD96 (CD96) (AA 22-503) protein (mFc-His Tag)CD96 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD96 (CD96) (AA 22-503) protein (His tag)CD96 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD96 (CD96) (AA 1-402) protein (GST tag)CD96 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD96 (CD96) (AA 22-503) (Active) protein (Fc Tag)CD96 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD96
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别名
- CD96
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背景
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Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), a nectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. The effect the cells with mutated CD96 protein lost adhesion and growth activities indicates that CD96 mutations may cause a form of the C syndrome by interfering with cell adhesion and growth.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: T-cell surface protein tactile; Cell surface antigen CD96; T cell-activated increased late expression protein; CD96
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分子量
- 58 kDa
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UniProt
- Q3U0X8
抗原
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