CD69 Protein (CD69) (Fc Tag,ECD)
Quick Overview for CD69 Protein (CD69) (Fc Tag,ECD) (ABIN7320166)
抗原
See all CD69 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD69 protein is labelled with Fc Tag,ECD.
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原理
- Recombinant Mouse CD69 Protein (Fc tag, ECD)
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序列
- Gly64-Arg199
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产品特性
- A DNA sequence encoding the mouse Cd69 (NP_001028294.1) (Gly64-Arg199) was expressed with the Fc region of human IgG1 at the N-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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CD69 (CD69) (AA 1-199) protein (His tag)
custom-made CD69 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD69 (CD69) (AA 1-199) protein (His tag)custom-made CD69 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD69 (CD69) (AA 62-199) protein (His tag)CD69 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD69 (CD69) (AA 62-199) protein (His tag)CD69 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD69 (CD69) (AA 90-199) protein (GST tag)CD69 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD69 (CD69) (AA 1-199) protein (GST tag)CD69 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD69 (CD69) protein (Fc Tag)CD69 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD69 (CD69) protein (His tag,ECD)CD69 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD69
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别名
- CD69
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背景
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Background: Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.
Synonym: 5830438K24Rik,AI452015,AIM,VEA,CLEC2C
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分子量
- 44.1 kDa
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NCBI登录号
- NP_001028294
抗原
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