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CD5L Protein (His tag)

This Recombinant CD5L protein is expressed in HEK-293 Cells.
产品编号 ABIN7320432
发货至: 中国
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Quick Overview for CD5L Protein (His tag) (ABIN7320432)

抗原

See all CD5L 蛋白
CD5L (CD5 Molecule-Like (CD5L))

蛋白类型

Recombinant

宿主

  • 10
  • 4
  • 2
小鼠

资源

  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

纯度

> 98 % as determined by reducing SDS-PAGE.
  • 标记

    This CD5L protein is labelled with His tag.

    原理

    Recombinant Mouse CD5L Protein (His Tag)

    序列

    Met 1-Val 352

    产品特性

    A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD5L (CD5 Molecule-Like (CD5L))

    别名

    CD5L

    背景

    AAC-11,AI047839,Aim,Api6,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CD5 antigen-like,CT-2,CT2,Cd5l,Pdp,SP-alpha,Sp-alpha,CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

    分子量

    38 kDa

    NCBI登录号

    NP_033820

    UniProt

    Q9QWK4
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