CD48 Protein (CD48) (His tag)
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Quick Overview for CD48 Protein (CD48) (His tag) (ABIN7320284)
抗原
See all CD48 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- This CD48 protein is labelled with His tag.
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原理
- Recombinant Mouse CD48 Protein (His Tag)
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序列
- Met 1-Arg 216
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产品特性
- A DNA sequence encoding the mouse CD48 (NP_031675.1) without the propeptide, corresponding to the amino acids (Met 1-Arg 216) was expressed with a C-terminal polyhistidine tag.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to bind human 2B4 and biotinylated recombinant mouse CD2 in functional ELISA.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD48
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别名
- CD48
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背景
- AI449234,AW610730,BCM1,BLAST-1,BLAST1,Bcm-1,CD48,MEM-102,SLAM Family Member 2,SLAMF2,Sgp-60,Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
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分子量
- 23.7 kDa
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基因ID
- 12506
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NCBI登录号
- NP_031675
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UniProt
- P18181
抗原
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