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CD48 Protein (CD48) (His tag)

This Recombinant CD48 protein is expressed in HEK-293 Cells.
产品编号 ABIN7320284
发货至: 中国
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Quick Overview for CD48 Protein (CD48) (His tag) (ABIN7320284)

抗原

See all CD48 蛋白
CD48

蛋白类型

Recombinant

生物活性

Active

宿主

  • 19
  • 10
  • 5
小鼠

资源

  • 12
  • 9
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 85 % as determined by SDS-PAGE
  • 标记

    This CD48 protein is labelled with His tag.

    原理

    Recombinant Mouse CD48 Protein (His Tag)(Active)

    序列

    Met 1-Arg 216

    产品特性

    A DNA sequence encoding the mouse CD48 (NP_031675.1) without the propeptide, corresponding to the amino acids (Met 1-Arg 216) was expressed with a C-terminal polyhistidine tag.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    1. Measured by its ability to bind human 2B4 in a functional ELISA.2. Measured by its ability to bind biotinylated recombinant mouse CD2 in a functional ELISA.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD48

    别名

    CD48

    背景

    Background: Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.Immune CheckpointImmune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: CD48; BLAST1; BCM1; SLAMF2;SLAM Family Member 2;AI449234; AW610730; Bcm-1; BLAST-1; MEM-102;Sgp-60

    分子量

    23.7 kDa

    NCBI登录号

    NP_031675
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