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CD38 Protein (AA 44-301) (His tag)

This Recombinant CD38 protein is expressed in HEK-293 Cells.
产品编号 ABIN7320976
发货至: 中国
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Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN7320976)

抗原

See all CD38 蛋白
CD38

蛋白类型

Recombinant

宿主

  • 28
  • 11
  • 5
  • 5
  • 1
Cynomolgus

资源

  • 20
  • 9
  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 44-301

    标记

    This CD38 protein is labelled with His tag.

    原理

    Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (His Tag)

    序列

    Leu44-Ile301

    产品特性

    Recombinant Cynomolgus CD38 is produced by our Mammalian expression system and the target gene encoding Leu44-Ile301 is expressed with a 6His tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD38

    别名

    CD38/ADP-ribosyl Cyclase 1

    背景

    ADP-ribosyl cyclase 1,CD38,T10,cyclic ADP-ribose hydrolase,CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

    分子量

    Calculated MW: 30.9 kDa

    Observed MW: 38-50 kDa

    UniProt

    Q5VAN0
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