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CD38 Protein (His tag)

This Recombinant CD38 protein is expressed in HEK-293 Cells.
产品编号 ABIN7194833
发货至: 中国

Quick Overview for CD38 Protein (His tag) (ABIN7194833)

抗原

See all CD38 蛋白
CD38

蛋白类型

Recombinant

生物活性

Active

宿主

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小鼠

资源

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HEK-293 Cells

纯度

> 97 % as determined by SDS-PAGE
  • 标记

    This CD38 protein is labelled with His tag.

    原理

    Recombinant Mouse CD38 Protein (His Tag)(Active)

    序列

    Leu 45-Thr 304

    产品特性

    A DNA sequence encoding the extracellular domain of mouse CD38 (NP_031672.2) (Leu 45-Thr 304) was expressed, fused with a C-terminal polyhistidine tag.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDPribose. The specific activity is >50,000pmols/min/ug.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Mouse
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Mouse
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile 20 mM MES, 0.15M NaCl, pH 6.5

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD38

    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

    Synonym: cADPr hydrolase 1, CD38 antigen (p45), CD38 antigen, CD38 Molecule, CD38, Cyclic ADP-ribose hydrolase 1, Cyclic ADP-ribose Hydrolase, EC 3.2.2.5, NAD(+) nucleosidase, T10,ADPRC 1-rs1,ADPRC1,Cd38,Cd38-rs1,I-19

    分子量

    31.3 kDa

    NCBI登录号

    NP_031672
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