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DCL1 Protein (Fc Tag)

This Recombinant DCL1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7321088
发货至: 中国
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Quick Overview for DCL1 Protein (Fc Tag) (ABIN7321088)

抗原

See all DCL1 (CD302) 蛋白
DCL1 (CD302) (CD302)

蛋白类型

Recombinant

宿主

  • 6
  • 4
  • 1
  • 1
大鼠

资源

  • 3
  • 3
  • 2
  • 2
  • 2
HEK-293 Cells

纯度

> 95 % as determined by SDS-PAGE
  • 标记

    This DCL1 protein is labelled with Fc Tag.

    原理

    Recombinant Rat CD302/CLEC13A Protein (Fc Tag)

    序列

    Met1-His165

    产品特性

    A DNA sequence encoding the rat CD302 (Met1-His165) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    DCL1 (CD302) (CD302)

    别名

    CD302/CLEC13A

    背景

    Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.

    Synonym: CD302

    分子量

    43.7 kDa

    NCBI登录号

    NP_001013938

    途径

    Regulation of Actin Filament Polymerization
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