DCL1 Protein (Fc Tag)
Quick Overview for DCL1 Protein (Fc Tag) (ABIN7320182)
抗原
See all DCL1 (CD302) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This DCL1 protein is labelled with Fc Tag.
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原理
- Recombinant Mouse CD302/CLEC13A Protein (Fc Tag)
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序列
- Met 1-His 156
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产品特性
- A DNA sequence encoding the extracellular domain of mouse CD302 isoform 2 (Q9DCG2-2) (Met 1-His 156) was fused with the Fc region of human IgG1 at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- DCL1 (CD302) (CD302)
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别名
- CD302/CLEC13A
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背景
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Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.
Synonym: 1110055L24Rik,AI159627
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分子量
- 42.6 kDa
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途径
- Regulation of Actin Filament Polymerization
抗原
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