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CD300a Protein (CD300A) (His tag)

This Recombinant CD300a protein is expressed in 人细胞.
产品编号 ABIN7318730
发货至: 中国

Quick Overview for CD300a Protein (CD300A) (His tag) (ABIN7318730)

抗原

See all CD300a (CD300A) 蛋白
CD300a (CD300A)

蛋白类型

Recombinant

宿主

  • 16
  • 5
  • 3
  • 1

资源

  • 11
  • 4
  • 4
  • 3
  • 2
  • 1
人细胞

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This CD300a protein is labelled with His tag.

    原理

    Recombinant Human CD300a/LMIR1 Protein (His Tag)

    序列

    Leu18-Gln178

    产品特性

    Recombinant Human Leukocyte mono-Ig-like receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu18-Gln178 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD300a (CD300A)

    别名

    CD300a/LMIR1

    背景

    Background: CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

    Synonym: CMRF35-Like Molecule 8, CLM-8, CD300 Antigen-Like Family Member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin Superfamily Member 12, IgSF12, Inhibitory Receptor Protein 60, IRp60, NK Inhibitory Receptor, CD300a, CD300A, CMRF35H, IGSF12

    分子量

    18.5 kDa

    UniProt

    Q9UGN4

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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