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CD300a Protein (CD300A) (Fc Tag)

This Recombinant CD300a protein is expressed in 人细胞.
产品编号 ABIN7320607
发货至: 中国

Quick Overview for CD300a Protein (CD300A) (Fc Tag) (ABIN7320607)

抗原

See all CD300a (CD300A) 蛋白
CD300a (CD300A)

蛋白类型

Recombinant

宿主

  • 18
  • 5
  • 3
  • 1
小鼠

资源

  • 11
  • 6
  • 4
  • 3
  • 2
  • 1
人细胞

纯度

> 95 % as determined by SDS-PAGE
  • 标记

    This CD300a protein is labelled with Fc Tag.

    原理

    Recombinant Mouse CD300a/LMIR1 Protein (Fc Tag)

    序列

    Leu28-Arg183

    产品特性

    Recombinant Mouse Leukocyte mono-Ig-like receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu28-Arg183 is expressed with a Fc tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD300a (CD300A)

    别名

    CD300a/LMIR1

    背景

    Background: LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.

    Synonym: CD300a,CD300a antigen,CMRF35H9, CD300a molecule, leukocyte immunoglobulin-like receptor,CD300 antigen-like family member A, CMRF35-like molecule 8,NK inhibitory receptor, Immunoglobulin superfamily member 12, IRp60,Inhibitory receptor protein 60, CLM8, CMRF-35H, IGSF12, IRC1, IRC2, LMIR1,CLM-8,MAIR-I,Clm8,MAIR-I,MAIR-Ia,mcpir1,MMAC8,Pigr4

    分子量

    44.3 kDa

    UniProt

    Q6SJQ0

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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