电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CD209b Antigen (CD209B) protein (His tag)

CD209B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320261
发货至: 中国
  • 抗原 See all CD209b Antigen (CD209B) 蛋白
    CD209b Antigen (CD209B)
    蛋白类型
    Recombinant
    宿主
    小鼠
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    His tag
    原理
    Recombinant Mouse CD209B/DC-SIGNR1 Protein (His Tag)
    序列
    Gln 74-Gly 325
    产品特性
    A DNA sequence encoding the extracellular domain of mouse CD209B isoform 1 (NP_081248.2) (Gln 74-Gly 325) was fused with a polyhistidine tag at the N-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD209b Antigen (CD209B)
    别名
    CD209B/DC-SIGNR1 (CD209B 产品)
    别名
    1810030I22Rik Protein, OtB7 Protein, SIGNR1 Protein, mSIGNR1 Protein, CD209b antigen Protein, Cd209b Protein
    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD209b, also known as SIGNR1, is a C-type lectin receptor. CD209b is present on most regions of mouse brain and found on microglia and dendritic cells but not on neurons or astrocytes. CD209b is implicated in the recently described SIGNR1 complement activation pathway, which operates against capsular polysaccharides in splenic marginal macrophages. CD209b in rat is homologue to SIGNR1 in mouse, both of which are found to mediate the uptake of dextran or CPS14 within the splenic marginal zone.

    Synonym: 1810030I22Rik,DC-SIGNR1,mSIGNR1,OtB7,SIGNR1

    分子量
    31.4 kDa
    NCBI登录号
    NP_081248
You are here: