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CD177 Protein (His tag)

This Recombinant CD177 protein is expressed in 人细胞.
产品编号 ABIN7318970
发货至: 中国

Quick Overview for CD177 Protein (His tag) (ABIN7318970)

抗原

See all CD177 蛋白
CD177 (CD177 Molecule (CD177))

蛋白类型

Recombinant

宿主

  • 8
  • 2

资源

  • 4
  • 4
  • 1
  • 1
人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This CD177 protein is labelled with His tag.

    原理

    Recombinant Human PRV1/CD177 Protein (His Tag)

    序列

    Leu22-Gly407

    产品特性

    Recombinant Human Polycythemia Rubra Vera Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu22-Gly407 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD177 (CD177 Molecule (CD177))

    别名

    PRV1/CD177

    背景

    Background: CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.

    Synonym: CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA-2a, NB1 Glycoprotein, NB1 GP, Polycythemia Rubra Vera Protein 1, PRV-1, CD177, NB1, PRV1

    分子量

    42.3 kDa

    UniProt

    Q8N6Q3
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