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CD164 Protein (CD164) (Fc Tag)

This Recombinant CD164 protein is expressed in HEK-293 Cells.
产品编号 ABIN7321109
发货至: 中国

Quick Overview for CD164 Protein (CD164) (Fc Tag) (ABIN7321109)

抗原

See all CD164 蛋白
CD164

蛋白类型

Recombinant

宿主

  • 8
  • 2
  • 2
  • 1
大鼠

资源

  • 4
  • 4
  • 2
  • 2
  • 1
HEK-293 Cells

纯度

(84.8+14.7) % as determined by SDS-PAGE
  • 标记

    This CD164 protein is labelled with Fc Tag.

    原理

    Recombinant Rat CD164/Endolyn Protein (Fc Tag)

    序列

    Met1-Asp160

    产品特性

    A DNA sequence encoding the rat CD164 (Q9QX82) (Met1-Asp160) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD164

    别名

    CD164/Endolyn

    背景

    Background: Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a novel 80- to 90-kD mucin-like molecule expressed by human CD34+ hematopoietic progenitor cells. Isoform 1 and isoform 3 of CD164 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 of CD164 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells. CD164 belongs to the CD164 family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. CD164 may play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. CD164 promotes myogenesis by enhancing CXCR4-dependent cell motility. This protein positively regulates myoblast migration and promotes myoblast fusion into myotubes. CD164 may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to bone marrow stroma and by negatively regulating CD34+hematopoietic progenitor cell growth.

    Synonym: CD164

    分子量

    41.3 kDa

    UniProt

    Q9QX82
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