Cathepsin S Protein (CTSS) (His tag)
Quick Overview for Cathepsin S Protein (CTSS) (His tag) (ABIN7320704)
抗原
See all Cathepsin S (CTSS) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cathepsin S protein is labelled with His tag.
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原理
- Recombinant Mouse Cathepsin S/CTSS Protein (His Tag)
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序列
- Val18-Ile340
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产品特性
- Recombinant Mouse Cathepsin S is produced by our Mammalian expression system and the target gene encoding Val18-Ile340 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin S (CTSS) (AA 1-331) protein (GST tag)
CTSS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin S (CTSS) (AA 24-340) protein (His tag)CTSS 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Cathepsin S (CTSS) (Active) protein (His tag)CTSS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Cathepsin S (CTSS) proteinCTSS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cathepsin S (CTSS)
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别名
- Cathepsin S/CTSS
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背景
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Background: Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).
Synonym: Cathepsin S, CTSS
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分子量
- 37.5 kDa
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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