Cathepsin D Protein (CTSD) (His tag)
Quick Overview for Cathepsin D Protein (CTSD) (His tag) (ABIN7320739)
抗原
See all Cathepsin D (CTSD) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cathepsin D protein is labelled with His tag.
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原理
- Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
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序列
- Ile21-Leu410
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产品特性
- Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin D (CTSD) (AA 21-410) (Active) protein (His tag)
CTSD 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Cathepsin D (CTSD) (AA 26-412) protein (GST tag)CTSD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin D (CTSD) (AA 67-403), (partial) protein (GST tag)CTSD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cathepsin D (CTSD)
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别名
- Cathepsin D/CTSD
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背景
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Background: CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
Synonym: Cathepsin D, CTSD,CPSD
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分子量
- 43.9 kDa
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NCBI登录号
- NP_034113
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途径
- Peptide Hormone Metabolism
抗原
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