CARTPT 蛋白
Quick Overview for CARTPT 蛋白 (ABIN7317276)
抗原
See all CARTPT 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human CART/CARTPT Protein
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序列
- Met 1-Leu116
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产品特性
- A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with five amino acids (DDDDK) at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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CART Prepropeptide (CARTPT) protein (GST tag)
CARTPT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CART Prepropeptide (CARTPT) protein (Myc-DYKDDDDK Tag)CARTPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CARTPT (CART Prepropeptide (CARTPT))
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别名
- CART/CARTPT
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背景
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Background: Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell.
Synonym: CART
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分子量
- 10.6 kDa
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NCBI登录号
- NP_004282
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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