CARTPT Protein (mFc Tag)
This Recombinant CARTPT protein is expressed in HEK-293 Cells.
产品编号 ABIN7317277
发货至:
中国
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Quick Overview for CARTPT Protein (mFc Tag) (ABIN7317277)
抗原
See all CARTPT 蛋白
CARTPT
(CART Prepropeptide (CARTPT))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 95 % as determined by reducing SDS-PAGE.
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标记
- This CARTPT protein is labelled with mFc Tag.
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原理
- Recombinant Human CART/CARTPT Protein (Fc Tag)
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序列
- Met 1-Leu116
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产品特性
- A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with the Fc region of mouse IgG1 at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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CART Prepropeptide (CARTPT) protein (GST tag)
CARTPT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CART Prepropeptide (CARTPT) protein (Myc-DYKDDDDK Tag)CARTPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CARTPT (CART Prepropeptide (CARTPT))
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别名
- CART/CARTPT
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背景
- CART,In RNAseq data from human islet donors, CARTPT expression levels correlated with insulin, exocytosis genes and key beta-cell transcription factors. Insufficient insulin release and hyperglucagonaemia are culprits in type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART, encoded by Cartpt) affects islet hormone secretion and beta cell survival in vitro in rats, and Cart (-/-) mice have diminished insulin secretion. Established a potential role for cocaine and amphetamine regulated transcript (CARTPT) in dominant follicle selection in cattle. CARTPT expression is elevated in subordinate versus dominant follicles, and treatment with the mature form of the CARTPT peptide (CART) decreases follicle-stimulating hormone (FSH)-stimulated granulosa cell estradiol production in vitro and follicular fluid estradiol and granulosa cell CYP19A1 mRNA in vivo.
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分子量
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Calculated MW: 36.3 kDa
Observed MW: 37 kDa
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基因ID
- 9607
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NCBI登录号
- NP_004282
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UniProt
- Q16568
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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