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CES2 Protein (His tag)

This Recombinant CES2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7194592
发货至: 中国

Quick Overview for CES2 Protein (His tag) (ABIN7194592)

抗原

See all CES2 蛋白
CES2 (Carboxylesterase 2 (CES2))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 8
  • 1
小鼠

资源

  • 4
  • 2
  • 2
  • 1
HEK-293 Cells

纯度

> 85 % as determined by SDS-PAGE
  • 标记

    This CES2 protein is labelled with His tag.

    原理

    Recombinant Mouse Carboxylesterase-2/CES2 Protein (His Tag)(Active)

    序列

    Met 1-Lys 557

    产品特性

    A DNA sequence encoding the extracellular domain of mouse CES2 (NP_663578.1) (Met 1-Lys 557) was expressed, with a polyhistidine tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to hydrolyze pnitrophenylacetate. The specific activity is >90,000 pmoles/min/μg.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CES2 (Carboxylesterase 2 (CES2))

    别名

    Carboxylesterase-2/CES2

    背景

    Background: Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

    Synonym: ces2A3

    分子量

    60.4 kDa

    NCBI登录号

    NP_663578
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