S100A8/A9 Complex (Calprotectin) Protein (His tag)
Quick Overview for S100A8/A9 Complex (Calprotectin) Protein (His tag) (ABIN7319332)
抗原
See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This S100A8/A9 Complex (Calprotectin) protein is labelled with His tag.
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原理
- Recombinant Human S100A8&S100A9 Heterodimer Protein (His Tag)
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序列
- Met 1-Glu93(S100A8)&Thr 2-Pro114(S100A9)
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产品特性
- Recombinant Human S100 Calcium Binding Protein S100A8/S100A9 Heterodimer is produced by our E.coli expression system and the target gene encoding Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES,10 % Glycerol,150 mM NaCl,2.5 mM EDTA, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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别名
- S100A8&S100A9 Heterodimer
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背景
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Background: S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
Synonym: S100A8/S100A9 Heterodimer
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分子量
- 11.7&13.2 kDa
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途径
- S100 Proteins
抗原
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