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S100A8/A9 Complex (Calprotectin) Protein (His tag)

This Recombinant S100A8/A9 Complex (Calprotectin) protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7319332
发货至: 中国
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Quick Overview for S100A8/A9 Complex (Calprotectin) Protein (His tag) (ABIN7319332)

抗原

See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 蛋白
S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

蛋白类型

Recombinant

宿主

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资源

  • 7
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This S100A8/A9 Complex (Calprotectin) protein is labelled with His tag.

    原理

    Recombinant Human S100A8&S100A9 Heterodimer Protein (His Tag)

    序列

    Met 1-Glu93(S100A8)&Thr 2-Pro114(S100A9)

    产品特性

    Recombinant Human S100 Calcium Binding Protein S100A8/S100A9 Heterodimer is produced by our E.coli expression system and the target gene encoding Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM HEPES,10 % Glycerol,150 mM NaCl,2.5 mM EDTA, pH 7.4.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

    别名

    S100A8&S100A9 Heterodimer

    背景

    Background: S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.

    Synonym: S100A8/S100A9 Heterodimer

    分子量

    11.7&13.2 kDa

    途径

    S100 Proteins
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