CALML5 Protein (His-GST)
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北京 101111
Quick Overview for CALML5 Protein (His-GST) (ABIN7317487)
抗原
See all CALML5 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CALML5 protein is labelled with His-GST.
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原理
- Recombinant Human CALML5/CLSP Protein (His & GST Tag)
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序列
- Met 1-Glu 146
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产品特性
- A DNA sequence encoding the human CALML5 (AAH39172.1) (Met 1-Glu 146) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Calmodulin-Like 5 (CALML5) (AA 47-146) protein (GST tag)
CALML5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calmodulin-Like 5 (CALML5) (AA 1-146) protein (GST tag)CALML5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calmodulin-Like 5 (CALML5) (AA 2-146) protein (His-SUMO Tag)CALML5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
Calmodulin-Like 5 (CALML5) protein (Myc-DYKDDDDK Tag)CALML5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 150 mM NaCl, 1 mM DTT, 0.5 mM GSH, 10 % glycerol, pH 7.8
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CALML5 (Calmodulin-Like 5 (CALML5))
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别名
- CALML5/CLSP
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背景
- CLSP,Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
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分子量
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Calculated MW: 44.2 kDa
Observed MW: 43 kDa
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基因ID
- 51806
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UniProt
- Q9NZT1
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途径
- Phototransduction
抗原
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