Calmegin Protein (CLGN) (AA 20-471) (His tag)
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Quick Overview for Calmegin Protein (CLGN) (AA 20-471) (His tag) (ABIN7318224)
抗原
See all Calmegin (CLGN) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 20-471
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标记
- This Calmegin protein is labelled with His tag.
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原理
- Recombinant Human Calmegin/CLGN Protein (His Tag)
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序列
- Glu20-Trp471
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产品特性
- Recombinant Human Calmegin is produced by our Mammalian expression system and the target gene encoding Glu20-Trp471 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Calmegin (CLGN)
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别名
- Calmegin/CLGN
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背景
- CLGN,Calmegin,Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.
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分子量
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Calculated MW: 52.9 kDa
Observed MW: 60 kDa
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基因ID
- 1047
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UniProt
- O14967
抗原
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