CAMK1D Protein (GST tag)
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Quick Overview for CAMK1D Protein (GST tag) (ABIN7317091)
抗原
See all CAMK1D 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CAMK1D protein is labelled with GST tag.
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原理
- Recombinant Human CAMK1D Protein (GST Tag)(Active)
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序列
- Met 1-Lys 385
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产品特性
- A DNA sequence encoding the human CAMK1D (NP_705718.1) (Met 1-Lys 385) was fused with the GST tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 70 nmol/min/mg using Autocamtide-2 synthetic peptide (KKALRRQETVDAL-amide) as substrate.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 127,054.94 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D) (AA 1-385) protein (His tag)
custom-made CAMK1D 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D) (AA 1-385) protein (His tag)custom-made CAMK1D 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D) (AA 1-385) protein (His-IF2DI Tag)CAMK1D 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D) (AA 1-385) protein (GST tag)CAMK1D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CAMK1D 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as sterile 50 mM Tris, 100 mM NaCl, 0.5 mM Reduced Glutathione, pH 8.0
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CAMK1D (Calcium/calmodulin-Dependent Protein Kinase ID (CAMK1D))
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别名
- CAMK1D
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背景
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Background: Calcium/calmodulin-dependent protein kinase or CaM kinases are serine/threonine-specific protein kinases that are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. CaM kinases activity can outlast the intracellular calcium transient that is needed to activate it. In neurons, this property is important for the induction of synaptic plasticity. Pharmacological inhibition of CaM kinases II blocks the induction of long-term potentiation. Upon activation, CaM kinases II phosphorylates postsynaptic glutamate receptors and changes the electrical properties of the synapse. Calcium/calmodulin-dependent protein kinase type 1D, also known as CaM kinase I delta, CaM kinase ID, CaMKI-like protein kinase, CKLiK and CAMK1D, is a member of the protein kinase superfamily and CaMK subfamily. It contains one protein kinase domain. CAMK1D is broadly expressed. It is highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. Engineered overexpression of CAMK1D in non-tumorigenic breast epithelial cells led to increased cell proliferation, and molecular and phenotypic alterations indicative of epithelial-mesenchymal transition (EMT), including loss of cell-cell adhesions and increased cell migration and invasion. CAMK1D is a potential therapeutic target with particular relevance to clinically unfavorable basal-like tumors.
Synonym: Calcium/calmodulin-dependent protein kinase type 1D; CaM kinase I delta; CaMKI-like protein kinase; CAMK1D; CaMK1 delta;CaM-K1;CKLiK
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分子量
- 69 kDa
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NCBI登录号
- NP_705718
抗原
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