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Cadherin-16 Protein (CDH16) (His tag)

This Recombinant Cadherin-16 protein is expressed in 人细胞.
产品编号 ABIN7318216
发货至: 中国

Quick Overview for Cadherin-16 Protein (CDH16) (His tag) (ABIN7318216)

抗原

See all Cadherin-16 (CDH16) 蛋白
Cadherin-16 (CDH16)

蛋白类型

Recombinant

宿主

  • 5
  • 2

资源

  • 3
  • 2
  • 1
  • 1
人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This Cadherin-16 protein is labelled with His tag.

    原理

    Recombinant Human Cadherin-16/CDH16 Protein (His Tag)

    序列

    Pro18-Ala786

    产品特性

    Recombinant Human Cadherin-16 is produced by our Mammalian expression system and the target gene encoding Pro18-Ala786 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Cadherin-16 (CDH16)

    别名

    Cadherin-16/CDH16

    背景

    Background: Cadherin-16(CDH16) is a single-pass type I membrane protein which contains six cadherin domains. Mature cadherin proteins consist of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium-dependent cell adhesion proteins and may contribute to the sorting of heterogeneous cell types. They preferentially interact with themselves in a homophilic manner in connecting cells. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development. CDH16 is composed of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain. However, it lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.

    Synonym: CDH16,Cadherin-16,Kidney-specific cadherin,Ksp-cadherin

    分子量

    84.6 kDa

    UniProt

    O75309
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