Cadherin-16 Protein (CDH16) (His tag)
Quick Overview for Cadherin-16 Protein (CDH16) (His tag) (ABIN7318216)
抗原
See all Cadherin-16 (CDH16) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cadherin-16 protein is labelled with His tag.
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原理
- Recombinant Human Cadherin-16/CDH16 Protein (His Tag)
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序列
- Pro18-Ala786
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产品特性
- Recombinant Human Cadherin-16 is produced by our Mammalian expression system and the target gene encoding Pro18-Ala786 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cadherin-16 (CDH16)
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别名
- Cadherin-16/CDH16
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背景
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Background: Cadherin-16(CDH16) is a single-pass type I membrane protein which contains six cadherin domains. Mature cadherin proteins consist of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium-dependent cell adhesion proteins and may contribute to the sorting of heterogeneous cell types. They preferentially interact with themselves in a homophilic manner in connecting cells. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development. CDH16 is composed of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain. However, it lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.
Synonym: CDH16,Cadherin-16,Kidney-specific cadherin,Ksp-cadherin
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分子量
- 84.6 kDa
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UniProt
- O75309
抗原
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