Cadherin 8 Protein (CDH8) (AA 1-621)
Our Local Distributor
北京 101111
Quick Overview for Cadherin 8 Protein (CDH8) (AA 1-621) (ABIN7194516)
抗原
See all Cadherin 8 (CDH8) 蛋白蛋白类型
宿主
资源
纯度
-
-
产品特性
- AA 1-621
-
原理
- Recombinant Rat Cadherin-8/CDH8 Protein
-
序列
- Met1-Met621
-
产品特性
- A DNA sequence encoding the rat CDH8 (NP_445845.2)(Met1-Met621) was expressed with six amino acids (LEVLFQ) at the C-terminus.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
Cadherin 8 (CDH8) (AA 1-799) protein (GST tag)
CDH8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cadherin 8 (CDH8) (AA 1-621) protein (His tag)CDH8 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Cadherin 8 (CDH8) protein (Myc-DYKDDDDK Tag)CDH8 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
-
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
有效期
- 12 months
-
-
- Cadherin 8 (CDH8)
-
别名
- Cadherin-8/CDH8
-
背景
- CDH8,Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Type I cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of five subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherin 8, also known as CDH 8, is a type II classical cadherin belonging to the cadherin superfamily. As mainly expressed in brain, CDH8 is found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts, and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Human Cadherin 8 is a 799 amino acid single-pass type Itransmembrane protein with a putative 29 aa signal sequence, and a 32 aa propeptide, a 560 aa mature extracellular domain, a 21 aa transmembrane domain and a 157 aa cytoplasmic domain. The human, mouse and rat proteins share approximately 98 % homology.
-
分子量
-
Calculated MW: 65.9 kDa
Observed MW: 76-85 kDa
-
NCBI登录号
- NP_445845
-
UniProt
- A0A8I6AFP6
-
途径
- Cell-Cell Junction Organization
抗原
-
