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Cadherin 13 Protein (CDH13) (AA 1-692)

This Recombinant Cadherin 13 protein is expressed in HEK-293 Cells.
产品编号 ABIN7321153
发货至: 中国
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Quick Overview for Cadherin 13 Protein (CDH13) (AA 1-692) (ABIN7321153)

抗原

See all Cadherin 13 (CDH13) 蛋白
Cadherin 13 (CDH13)

蛋白类型

Recombinant

宿主

  • 7
  • 4
  • 2
大鼠

资源

  • 10
  • 2
  • 1
HEK-293 Cells

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-692

    原理

    Recombinant Rat Cadherin-13/CDH13 Protein

    序列

    Met1-Ala692

    产品特性

    A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Cadherin 13 (CDH13)

    别名

    Cadherin-13/CDH13

    背景

    CDH13,CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.

    分子量

    Calculated MW: 74.3 kDa

    Observed MW: 84-96 kDa

    NCBI登录号

    NP_620244

    UniProt

    A0A096MK38

    途径

    EGFR Signaling Pathway, Cell-Cell Junction Organization
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