Cadherin 12 Protein (His tag)
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- 抗原 See all Cadherin 12 蛋白
- Cadherin 12
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Cadherin 12 protein is labelled with His tag.
- 原理
- Recombinant Human Cadherin-12/CDH12 Protein (His Tag)
- 序列
- Met 1-Ala 605
- 产品特性
- A DNA sequence encoding the pro form of human CDH12 (NP_001783.2) extracellular domain (Met 1-Ala 605) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product Cadherin 12 蛋白
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Cadherin 12 (AA 55-609) protein (MBP tag)
Crystallography grade 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Cadherin 12 (AA 1-794) protein (GST tag)宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cadherin 12 (AA 372-470) protein (GST tag)宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cadherin 12 (AA 56-605), (partial) protein (His tag)宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM sodium citrate, 50 mM NaCl, 2 mM CaCl2, pH 6.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Cadherin 12
- 别名
- Cadherin-12/CDH12 (Cadherin 12 产品)
- 别名
- CDHB Protein, Cdhb Protein, RGD1566350 Protein, cdh12 Protein, cadherin 12 Protein, cadherin-12 Protein, CDH12 Protein, Cdh12 Protein, LOC570372 Protein
- 背景
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Background: Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic binding partners, catenins. The cadherin/catenin adhesion system plays key roles in the morphogenesis and function of the vertebrate and invertebrate nervous systems. Furthermore, this system is involved in synaptic plasticity. Recent studies on the role of individual cadherin subtypes at synapses indicate that individual cadherin subtypes play their own unique role to regulate synaptic activities. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. It has been observed that cells containing a specific cadherin subtype tend to cluster together to the exclusion of other types, both in cell culture and during development. Cadherin-12 also known as CDH12, is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-12 appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Synonym: CDHB
- 分子量
- 66 kDa
- NCBI登录号
- NP_001783
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